Key Largo to Key West: Your Unforgettable Florida Road Trip

Key Largo to Key West is the ultimate road trip that takes you on a scenic journey through the Florida Keys, showcasing the best of both islands. Starting from Key Largo, you’ll begin a picturesque drive along the Florida Overseas Highway, a 113-mile route that connects over 40 islands. This famous highway leads you from Key Largo all the way to Key West, giving you the opportunity to enjoy the stunning views of the Gulf of Mexico, Atlantic Ocean, and the incredible Florida Bay.

On your Key Largo to Key West adventure, you’ll visit tropical gems like Biscayne National Park and the stunning Florida Reef, the third-largest coral reef in the world. Along the way, you’ll pass beautiful beaches, quaint towns, and scenic landmarks, making it a perfect road trip for nature lovers, history buffs, and beach enthusiasts. Don’t miss iconic stops like Key West Pride, Coral Reef, and the charming Key West restaurants, where you can indulge in delicious local food.

This road trip is one of the best ways to experience the true beauty of the Florida Keys, from the peaceful beaches of Key Largo to the vibrant and lively atmosphere of Key West. Whether you’re snorkeling in the crystal-clear waters, visiting historical landmarks, or enjoying the Key West nightlife, the Key Largo to Key West route offers endless unforgettable moments.

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Explore the Best of Florida: Key Largo to Key West Road Trip

Start your adventure with the Key Largo to Key West road trip, an iconic journey along the scenic Florida Overseas Highway. As you travel through the enchanting Florida Keys, you’ll experience diverse landscapes, from vibrant beaches to charming local towns. This route is a perfect blend of tropical beauty, exciting outdoor activities, and rich culture, offering something for every type of traveler. Whether you’re a nature lover, a foodie, or a history enthusiast, the drive from Key Largo to Key West ensures a memorable experience at every mile.

By exporting this map into Google Maps, you’ll have easy access to all the favorite spots that make this road trip unforgettable. Whether you’re seeking a tropical vacation, great places to eat, or unique Florida destinations, this guide has it all covered. With restaurants and bars scattered along the way, you’re sure to have an amazing time exploring Key Largo, Key West, and everything in between!

Essential Packing Items for Your Key Largo to Key West Adventure

If you’re gearing up for your Key Largo to Key West road trip, packing wisely is key. The weather is mostly warm throughout the year, so you can rely on comfortable clothing like shorts, t-shirts, and flip flops. However, be prepared for cooler evenings by packing a sweater or jeans just in case.

Sunscreen: Your Ultimate Protection in the Florida Sun

No matter the time of year, sunscreen is a must for your adventure. I highly recommend Super goop! and their amazing matte screen and unseen sunscreen. Protect your skin with a high SPF—you’ll thank yourself later after all those sun-filled days exploring Key West and Key Largo.

Bring Your Own Snorkel Gear for Ultimate Freedom

Snorkeling is a top activity in the Florida Keys, so make sure you have your own snorkel gear if you plan to spend a lot of time in the ocean. While most snorkel tours offer equipment, having your own gear will make your experience even more enjoyable and hassle-free.

Capture the Magic with a GoPro

Capture the magic of the Florida Keys underwater with a GoPro! From tropical fish to mesmerizing coral heads, you’ll want to record every moment. A floating hand grip is also a must to ensure you don’t lose your camera during those thrilling moments.

Stay Safe and Stylish with Polarized Sunglasses and a Hat

Keep your eyes safe from the sun’s glare with polarized sunglasses. They’ll help you see wildlife in the ocean more clearly while also protecting your eyes. Pair them with a comfy hat for additional sun protection.

Perfect Your Outdoor Adventures with Water Shoes

A good pair of water shoes is essential for your Key Largo to Key West road trip. Choose something like Reef sandals that are waterproof and perfect for activities like kayaking, snorkeling, and exploring the beautiful Florida Keys.

Where to Stay in the Upper Keys

The Upper Keys, including Key Largo and Islamorada, are home to a variety of accommodations, each offering a different vibe. Whether you’re seeking a budget-friendly stay or a luxurious retreat, this region has it all. Here are some of the best options for your Florida Keys road trip.

Budget-Friendly Accommodation: Kona Kai Resort

If you’re looking for a peaceful retreat away from the crowds, Kona Kai Resort is perfect. This budget-friendly resort offers just 13 bungalows, making it a cozy and intimate choice for those who prefer a quieter stay. With amenities like a pool and gallery, it’s a great place to relax after a day of exploring the Keys.

Mid-Tier Comfort: Islander Resort

For those who want more amenities while still enjoying a laid-back atmosphere, Islander Resort is a fantastic mid-tier option. With 114 rooms and suites, this resort offers fun activities like bicycles and beach games. It’s perfect for families or anyone looking for a resort with plenty of on-site things to do.

Luxury Escape: Caribbean Resort

If you’re after luxury, Caribbean Resort won’t disappoint. This resort offers Caribbean-style homes, a stunning zero-entry pool, and a marina with a fishing pier. Whether you’re lounging by the pool or exploring the surrounding area, it’s a beautiful setting for those seeking a more upscale experience.

Upscale Resort: Playa Largo

For those who prefer ultimate luxury, Playa Largo in the Upper Keys is a must. Part of the Autograph Resort collection, it features beachfront dining, a luxurious pool, and an array of activities. It’s the perfect spot for those who want to indulge while enjoying the stunning beauty of the Florida Keys.

Day 1: Everglades National Park: A Wildlife Adventure

If you’re traveling from Key Largo to Key West, don’t miss a visit to Everglades National Park! This massive park is home to amazing wildlife like manatees, American crocodiles, and alligators. Start your day early at the Ernest F. Coe Visitor Center, which is just a short drive from Homestead. From here, explore Highway 9336 to visit Shark Valley and the Flamingo area. You can walk the Anhinga Trail, where you’ll likely spot wildlife, or take a peaceful stroll through the Mahogany Hammock boardwalk trail.

For an exciting afternoon, head to Shark Valley, one of the best spots for wildlife viewing in the park. Don’t forget to experience a thrilling airboat ride through the wetlands to get a closer look at Everglades wildlife! Whether you’re spotting alligators or just enjoying the Florida wetlands, this is a must-see stop on your road trip.

Day 2: Scuba Diving, Snorkeling & Relaxation in the Upper Keys

The Upper Keys, including Key Largo and Islamorada, are perfect for diving enthusiasts and nature lovers. If you’re scuba diving certified, don’t miss the chance to dive into iconic spots like Spiegel Grove or Molasses Reef. Alternatively, for a more relaxed experience, opt for a snorkeling tour around the Alligator Reef Lighthouse or John Pennekamp Coral Reef State Park. These sites are known for vibrant tropical fish, nurse sharks, octopus, and the occasional dolphins. Exploring Florida Keys wildlife beneath the water is truly an unforgettable experience.

After a thrilling day on the water, head to Islamorada for a well-deserved break at the Tiki Bar in Postcard Inn. Here, try the famous rum runner with a floater, a signature drink that has become a must-try for visitors. Unwind by the pool, relax in a hammock, and enjoy the perfect sunset views by the bayside. For dinner, indulge in a meal at one of Islamorada’s best restaurants, such as Lorelei Restaurant and Cabana Bar or Square Grouper, both offering incredible coastal dining with stunning views of the Florida sunset.

Day 3: Adventure, Wildlife, and Relaxation in the Florida Keys

On Day 3 of your Key Largo to Key West adventure, make your way to Robbie’s of Islamorada, famous for its tarpon feeding experience. After feeding the fish, rent a kayak and enjoy a peaceful backcountry tour through the mangroves, where you’ll get a close-up view of the diverse wildlife that calls the Keys home. For an adrenaline rush, hop on a jet ski tour around the coastline, where you may even spot some dolphins.

In the afternoon, consider visiting Dolphins Plus, a non-profit rehabilitation center where you can enjoy an ethical swimming with dolphins experience, making this a truly memorable encounter. Afterward, take a break and explore the souvenir shops like Shell World and Rain Barrel for some Florida keepsakes. Wrap up your day with a sunset and a Key Largo sunset cruise before enjoying a relaxing bottom fishing session at your hotel’s fishing dock, where you can try your luck with shrimp or ballyhoo as bait.

Day 4: Exploring Biscayne National Park and Water Adventures

On Day 4, head to Biscayne National Park just south of Miami, where you can explore the beauty of Boca Chita Key. The park is famous for its stunning reefs, shipwrecks, and rich marine life, making it perfect for a snorkeling adventure. Paddle boarding in Jones Lagoon offers a peaceful way to see the vibrant wildlife, while the Biscayne National Park Institute offers a range of eco-adventures, including the popular Sail, Paddle, Snorkel & Island Visit and a small group snorkel experience.

For a more personalized experience, consider booking a private charter through companies like Explore Miami Boat Rental, allowing you to customize your trip and visit hidden gems at your own pace. If you’re traveling with a family or prefer a group tour, there are plenty of options available, but remember to plan ahead since these tours can fill up quickly. Whether you’re looking for an action-packed adventure or a relaxing day on the water, Biscayne has something for everyone.

Day 5: Exploring the Middle Keys on Your Road Trip to Key West

Day 5 of your Key Largo to Key West road trip takes you through the Middle Keys along the scenic Overseas Highway. A must-stop is the Turtle Hospital in Marathon, where you can learn about efforts to rehabilitate sea turtles. From there, head to Bahia Honda State Park, where for just $8, you can enjoy the beach, snorkeling, and the view of an old railway bridge that adds a touch of history to the natural beauty. For a more active day, rent kayaks or paddle boards to explore the area’s pristine waters.

On the way, don’t miss the National Key Deer Refuge on Big Pine Key, where you can spot the endangered Key deer in their natural habitat, particularly near No Name Key. This area provides an incredible opportunity for wildlife watching and is a highlight for nature lovers traveling the Florida Keys. After a day of adventure, relax and enjoy the Florida Keys wildlife while staying in one of the many Key West hotels.

Day 6: Adventure and Sunset in Key West

On Day 6 of your Key Largo to Key West journey, it’s time for some adventure! Start your day with a Day trip to Fort Jefferson at Dry Tortugas. You can get there by taking the Yankee Freedom ferry or splurge on a seaplane ride for a truly unique experience. This historic site, originally built during the Civil War, once held prisoners and now offers incredible views and fascinating history. Don’t miss exploring the fort’s grounds and enjoying some snorkeling nearby.

In the afternoon, head back to Old Town Key West to soak in the vibrant atmosphere. Spend some time at Mallory Square to experience the famous Sunset Celebration, where you’ll find street vendors and performers creating a lively atmosphere as the sun sets over the Gulf. Afterward, grab dinner at Hot Tin Roof at Ocean Key Resort, offering amazing views and delicious food. Finish the night by exploring Duval Street—the heart of Key West nightlife—where you can enjoy tropical vacation vibes and maybe even catch a live performance.

Day 7: Bikes, Brunch, and Sunset in Key West

On Day 7 of your Key Largo to Key West road trip, start your morning with a delicious brunch at Blue Heaven, one of the best spots in Key West. The waffles and lobster Benedict are incredible, and you can’t miss the Key Lime Pie that’s as big as your head! After filling up, rent bikes from Eaton Bikes to explore Key West on two wheels. It’s a bike-friendly destination with plenty to see. Cycle over to the Southernmost Point sign for a classic photo op, then head to the Key West Lighthouse and Ernest Hemingway’s House to immerse yourself in the island’s history.

In the afternoon, relax at Smathers Beach or take a ferry to Sunset Key, where you can have lunch or dinner at Latitudes Resort. Afterward, book a sunset booze cruise to end your day with bottomless rum punch, live music, and delicious appetizers while cruising around the Keys. The sunset views over the water are absolutely stunning, making this the perfect way to wrap up your day in romantic Key West.

Day 8: Heading Home from Key West

On the final day of your Key Largo to Key West road trip, it’s time to head back to Miami or Fort Lauderdale. If you have a morning flight, I highly recommend leaving Key West the night before and staying at a hotel near the airport. The traffic in the Florida Keys can be unpredictable, and with one road in and one road out, delays are common. If you’re flying out of Miami, be sure to give yourself plenty of time, especially if you’re traveling during Miami rush hour. For an afternoon flight, allow extra time, as the drive can be slower due to traffic. To avoid stress, plan ahead and consider staying at an airport hotel for convenience.

Conclusion:

The Key Largo to Key West road trip is a must for anyone looking to explore the breathtaking beauty of the Florida Keys. From the tropical waters of Key Largo to the vibrant streets of Key West, this adventure offers endless opportunities for wildlife encounters, scenic drives, and unforgettable experiences. You’ll snorkel among vibrant reefs, enjoy the lively atmosphere of Key West, and discover hidden gems along the way. Whether you’re diving into the Everglades, kayaking through mangroves, or savoring local seafood, this trip is the perfect way to experience the best of Florida. Don’t forget to plan ahead, as traffic can be unpredictable, especially when heading back to Miami or Fort Lauderdale. This road trip will create lasting memories, so start packing!

FAQS:

Q: Is it worth driving from Key Largo to Key West

A: Absolutely! The scenic drive along the Florida Overseas Highway offers stunning ocean views and unforgettable stops, making it a must-do road trip.